European Patients Smart Open Services - epSOS (previously known as S.O.S. - "Smart Open Services") is a Europe-wide project organized by 27 beneficiaries representing twelve EU-member states, including ministries of health, national competence centres and numerous companies.

This makes it the  first European eHealth project clustering such a large number of countries in practical cooperation.

The overarching goal of epSOS is to develop a practical eHealth framework and an Information & Communication Technology (ICT) infrastructure that will enable secure access to patient health information, particularly with respect to basic patient summaries and ePrescriptions between different European healthcare systems.